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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59d6fab08217d50e384c1d233b5636e6b0faba7c8b50f23a1594f86ee4efdc7f' 
  AND token = 'RA3dJpC8owCXh/gRei7a21ovM1m65rJvRxj08Fwsx6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}