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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b563ccb9a64897f7b4395df24c10f62a5956f745f3e6dd526f106ca8ba53d897' 
  AND token = 'o0uUfrs4DdyFhij/0uYbBhdx3Hz3FiAkyNNiJ8WaMvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}