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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01290930d04bfec5c1a3b50dba4b136d42873dfc3b26cd731817464e3018a26c' 
  AND token = 'aM/UC2n1KbnuAu7hqyZzKzjMCM8RIS4mnVN6QKWtRZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}