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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b53b5edc6fd9c0d731ee1f2a0f859de5dbd7a096b6638cf8e11898e693f5d6f' 
  AND token = 'sy6+KQxFzrq6G9AgqwCdXOn9At8femrkRp2M9sAG/i0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}