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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b9ae1a7d83dc164203bc25ca61346009a23014e9493a2f67e47c45bd8117518' 
  AND token = 'MA53gLIawUyGqV84tgcN9w+Q8MNWvFUziDILHaFDnNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}