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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '000d74cff64819ee631ea337ac8ef20e3ea002d5d1e86ae61d9b26c13f60e391' 
  AND token = '4wEq2mXmYw3vinAYwZgpdUGlfwu+IQy9bHFEdL0YWLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}