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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a85147b37f47d50c7c55afed1f52e6970b70436facb99a5e0fec28fe9234396' 
  AND token = 'U7s9PxB6pnM4CE+dKW4/0F17JORmDl9v3CdEKW4hBys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}