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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '166becf6db45ef7cd2820b8f6dbc2e71cc56c0c9f776c1902a64d9edb53edb7d' 
  AND token = 'WAE6X3qssJYkgYMfftsVUkTkNrm+NfjyzWU1ssrS8/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}