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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cd40367c910b0736025e0f8d8b20e25444cfbafa6eb4b15b153fb897192e74e' 
  AND token = 'xmWpeiO14UUVwBX1xzKQ3dPHtdSaH0CaYnZTdq+uCWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}