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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69e3449a8a1607e86e1a8ae9ff2edd89bb40c0cf752a08f2587e20edd527e99c' 
  AND token = 'Cq+hXDXmDoNUFT4Brjr5a9hC5cMjHsfUEpnbhov2dDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}