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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c2e943254976b36f654fb999cb065402bf9a88e7ec79fbdab1e4123bc94820c' 
  AND token = '9yr2BX/eeSYZ5204zsATgnId/vBoyDV6jNDFmtUomSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}