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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afdf52186bef73f5b43ca8b02c77a1c131feff23a45e6e20e9d68bc7a1fcb3c1' 
  AND token = 'QJny+p5IXo4FcR8ioEuEgj65OLAhxSDdTZucdmuGJ0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}