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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e695805d2ec6d38cc2fd548a9e678901f51f2d1a074166047f33147768d8f68' 
  AND token = 'ia0gYeVzYLoWVvASIS4r6/8gpNlZ2d2iOhRY0+h7uA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}