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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b1ddb1081b396613e99c5fb2035b3272f3b3a9e277cf7df78492248c80354f5' 
  AND token = 'hi+nCB6PVp7m4uRHkjphASn74wQl7Msl9d29rIS5QIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}