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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2ca3ae3e49c2b2ba88db0774cc18ea754ec8b27add3784b0d78bddd4bbed7dc' 
  AND token = 'JnRAawxgQKQaDGNC1VnjMBhW0e2IcvoJ+s7HFIPMF1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}