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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e97875960d68c9e5df1e2cee4cb5af098e933441ca82f4a2433ca2f00859da' 
  AND token = 'PMeQWDE4Fel7h9icBkhg+3u1Yy6h5u3ASNlSqpFfP1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}