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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cde51f1797ec1a3713674dcb8f5bb9705cd9700ad1856209a7f1b7e8ba5b10bd' 
  AND token = 'jar3c+d0EtyAnVQeQPYpIAN/IwM9x1fyTWrgMXc1zWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}