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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24b50acc69574763f162f937496bbe1d62244e92a056b65345f03565c39e8553' 
  AND token = 'K6R0ACDX8GmSDoUcv7/xyDzGJ207q4mAeoZ3hl8VMKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}