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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be04ac2bd614059b2d99d96a696d18e0c572591ee61c216d11489b13330d19cb' 
  AND token = 'HwT4eoKJNDzN0p35pGkeROUYoYkaYpkVfIXZ3w427dA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}