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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581476bc4e3deb27a28b718f6154b608ff7741b9410b2b565421ffe252c14f11' 
  AND token = 's6XxxTnDnxKfYPSkLiQzJXFxjd3my25FMqRE2lh8iII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}