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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '247072a9761f309730165ae3a429a1dbc08a567e06f9cc5aa337b52a1f9358f9' 
  AND token = 'Em1DV3fICNBliXfNs0t3J41YT67E8/UYGZjrwmnPbTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}