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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de0bf0b4b0babfa21437dad8248c8da6c2f1439aaa92b2b0ce18743cf32782d4' 
  AND token = 'NAUpgKGGYe7XzKpt0mz7R1+4kAcy7Pxu+8W1bPFhAd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}