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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727181030106b0c2dcf6dfeb633be68892734ad6c7c88b192a04b5169392a8ce' 
  AND token = 'fQA3vCKBT4P7tOJ5diHiXpL6hApRX5R9QvLjwV2X+cA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}