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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74b4b2019ef7b3acece6cd89488ba0bf18e9f08730fc8305fed12d3cab02b734' 
  AND token = 'lB7/Avv2cbcBDnQ7l+re1hSp2cDmbCl9XkgRZd+wSic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}