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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '477f083fef21e9fece323e73c88014ca742184ae201901ae69f5c8bf36e0d306' 
  AND token = '/IdKqvos20GFc4vGL1kCfroDEPRZhdyM7p3hsvbbG0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}