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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79e285fb60d6df75e7e8941ba0cd857d1c29a146df272f0c4a04448882812b5b' 
  AND token = '8zLUX3Y6kQXVo2vIaymQrUt9jhkZi1NlvDODUOagdLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}