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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '856e0f315e7ff40b995b0750bb3a77b04dbb9242b33c0c15e6348dc1a8f67501' 
  AND token = 'i/c7P8CHC4SCRUtzrI9p1PMWCQm6ZuUE2+qH7ESgGl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}