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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f614b4ff83a226f1a9e6046b8185bc1336b1a003075212369cf6b1221403deb8' 
  AND token = 'v1TAOmY1B4uR+Nx2yEjcxZBOPSu4tD32CjT4Q5f6Kfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}