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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a6f5e3bee3fcbd4c2bc4a76d2e023896bb658a59c026f5722c99a6449680daf' 
  AND token = 'SgAfQmLeEzG2V63n4FtTRzE2uHqeA721d65rZp1MKHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}