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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16f4fcefb099b8db3b9f98542ea4deda22fb218c982f6ecf51c1ca0a7a5525ba' 
  AND token = 'yvXIRN4y+AvGtK6zE3XmapzMhaUdsZIrw3s7dwsMnK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}