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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59583c68cd7ace0590c21c09c80f7686adee2684eb80b7f20d2f35b181d08d4f' 
  AND token = 'CpUDeYCiAmo0GY5944gqeMa3o+CilWaRYEyWHYbZjNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}