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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01a8677c4e8bf3fcb748f410024d13bf82b25cf424775468cffd72e8922ef8c7' 
  AND token = 'SV/H0zlJLX62tBe8UQCf3ZUp1OTeQGmG+cb4XmBHkHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}