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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af221d3c59461876b2cc86a7c0f5ae95bd3b0d2617a5acf36601e2ad0a098f57' 
  AND token = 'cEIYBgYVj4MLRVosjoMkN2CoUniMNKPS9IWF+NGRjlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}