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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21cd0673fc908d9564fc53d1d323ee925a6af049adf43c6e2d3268c4273c3df5' 
  AND token = 'bxZ1Pncv00m3Qq0pDK2byUsoVL7TDmKVtg4QhSJr4No=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}