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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc430af3352cc9066e2ae320f335ffb08f253ae86d1e5c1673af20cf63cddd80' 
  AND token = 'R/Vptwl6R4oMNcMrgu65Xnfjn56ZRpJc5rWnqMdF20E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}