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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7227298782bb288266c17847075f5f0a8e48d36bcf4b12a0d1147d60226e4756' 
  AND token = 'HPWs5kU2xTmqaIPKW6Eh4Hv1Wt2Vu6g9PKmobjsM3fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}