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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8f1c197a5b006dbdb906276410ab7bb78ecf10860bf9f0a044b6b63d3e697e4' 
  AND token = 'lt5/cm9UmCBnT5quddjK2vKZfWP4O8BsnEMZfiLUdRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}