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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44aabdffdae37c66a011e69cc7fc8e6d4de473a206371f95735eb2a430021f56' 
  AND token = 'KbDdq+YdNA91Uah+gnQCJ+WDTihP77NmwkSidg71H18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}