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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c2471a710cbec4b65bc1b9fda7cc2f84b25b6505eee0739d1000663e6c124bc' 
  AND token = 'pGLUKGXm6m0oXf1GsTsjlcPcKF5ajio5RC7lM6NEbBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}