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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3a5729d4e40b98419fc929e67282136b293b12e6735ce15cce14a5779b6ec9f' 
  AND token = '6ucxlvlgFZic6m76ZVR/31yy2VXVJRmAB5/DD0p5Ifw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}