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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bedc57776e28e4b8f0daec66926e1ce59512f1eb950a8ca161b2a9f320e1d15' 
  AND token = 'u3l2CnQUmdBfgTv6A9h6yyCUDO2vg1xepOX0sMEGD7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}