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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65ee8d19e0d806ba4959ceb5208635127491314b8ff96f0e916662c7867e042' 
  AND token = 'OBNL4iZHjQrpKAdOmXknNuc1DpYzbhtMwmZEuqvfIdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}