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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b389f2d6477a3f21d38a92866c3e84cc8a74bd93a162400773dc9a6e6a5a4e2' 
  AND token = 'B6r7XsDBVcy2xTf9nfWzGdoCBPaF77eNL6WOrRwwZlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}