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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c3fb18f33e4684991587b621820934991d01e94d2f322e84ce20693427768de' 
  AND token = 'oly9QuYZBoi+J2n778IZawloX7WMoY2kFV3brLzLojI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}