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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c57b5c732b38f2f1f2969908c1f2c8c5e59b47c94e03ba2e9390796f5031749' 
  AND token = 'Rpo+Cc+LOjDMrvyCT1egDeBD5igOtDGjSgtkiVAyZBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}