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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d4cb52f973517da8121c4f74cb2ef5f1bb29d39fb945f015f2b12089f40a800' 
  AND token = 'ParMG1qWSrEjFlo/kTC/kzZcEGxnBt2EX3W0MVEogO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}