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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c35341c16fbab89eef2d13d53b310c47d1503db78784eccfbae845271cec0f7' 
  AND token = 'ze8gSLfPz+rqMstwp2Z5bb8OYoGGGZc9unzvCK9PxyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}