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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36956ff6ca620a4a508e0837226076790cb5c4fe3326e08b4e96964e62ec7985' 
  AND token = 'QgivbhFh6JaBhLK0rGmf7D24aqRnHh16GjMoKAXPHDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}