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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f81269f0ab2ac204d00100dea81edac21ee0351a71ab6aa193572e1cef5f3701' 
  AND token = '+e7/CkuCS5+ax9dwbQRrk2HJoE/H0wpEoI86lGPbcxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}