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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af01c89983d261975cded391fa82908983f8edf019e77798d9a02b5492f0278b' 
  AND token = 'YwCYCEll67W0pM81qFFYCJ/gBpo5ySA6553QOa/rU7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}